Midstream Health, the autonomous financial operations platform for health systems, has been named to Fast Company’s 2026 Next Big Thing in Tech list in the Enterprise category. The annual list recognizes technologies with the potential to shape their industries over the next five years. Midstream was recognized for an AI platform that connects revenue and cost in one intelligent system, continuously identifying and acting on opportunities to recover missed dollars, reduce spend, and improve margin.

Health systems negotiate value every day across supply, pharmacy, and payer contracts, but much of it never reaches the P&L. Pricing terms go unenforced, rebates go unclaimed, and underpayments go undetected because the conditions for collecting are buried across contracts and disconnected operational systems.

Midstream turns fragmented contract and operational data into a continuously validated financial record, then deploys domain-trained AI agents to reconcile it against live transactions, prioritize findings by financial impact, and carry opportunities through to realized dollars. Rather than simply showing finance teams where a problem exists, Midstream is built to help resolve it.

“Health systems have a leaky set of financial pipes, but they lack the visibility and capacity to find those leaks and close them,” said Sumit Kadakia, Co-Founder and CEO of Midstream Health. “Across American health systems, roughly $1 trillion flows through those pipes every year, making this a critical problem for the future of healthcare. Fast Company’s recognition reinforces that solving hard, foundational problems like this is where AI can have the greatest impact. That is what Midstream was built to do: identify where value is being lost, resolve it, and put those dollars back into patient care.”

Midstream’s platform now optimizes financial decision-making across health systems representing more than $88 billion in annual operating expenses and 250 hospitals, including CommonSpirit Health, Houston Methodist, and Mount Sinai Health System. Across its customer base, Midstream has identified more than 1,500 recoverable cases this year and is on pace to reach $100 million in client savings by the end of 2026. Its agents run around the clock across supply chain, pharmacy, and managed care, surfacing opportunities while there is still time to act on them.

Fast Company’s Next Big Things in Tech recognizes innovative technologies developed by established companies, startups, and research teams that are making meaningful progress toward transforming the lives of consumers, businesses, and society. This year’s honorees span industries, with each innovation demonstrating the potential to create significant impact in the years ahead.

“The most exciting technology innovations are the ones that move beyond promise to demonstrate real potential for impact,” said Brendan Vaughan, editor-in-chief of Fast Company. “The companies and teams recognized on this year’s list are tackling ambitious problems with new ideas, products, and approaches that have the potential to fundamentally shape the years ahead.”

To learn more, visit www.midstream.health. For more information or to view the complete Fast Company 2026 Next Big Things in Tech list, visit here.

About Midstream Health

Midstream is the autonomous financial operations platform purpose-built for health systems. Its domain-trained AI agents connect revenue and cost to continuously identify and recover margin health systems have already earned, turning fragmented pricing, rebate, reimbursement, and operational data into financial action. Across supply chain, pharmacy, and managed care, Midstream helps health systems move beyond dashboards and point solutions to continuously find, validate, and recover financial value. Midstream is backed by organizations including Andreessen Horowitz (a16z) and CommonSpirit Ventures. Learn more at www.midstream.health.

About Fast Company

Fast Company is the only media brand fully dedicated to the vital intersection of business, innovation, and design, engaging the most influential leaders, companies, and thinkers on the future of business. Headquartered in New York City, Fast Company is published by Mansueto Ventures LLC, along with fellow business publication Inc. For more information, please visit fastcompany.com.

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